Explain AP Biology Cellular Communication Terms Flashcards

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Signal transduction pathway
The recieved signal is converted to a specific cellular response in a series of steps
Local regulators
Messenger molecules that travel only short distances and influence cells in the vicinity
Hormones
Used for long distance signaling
Ligand
A molecule that specifically binds to another molecule
G protein coupled receptors
comprise a large protein family of transmembrane receptors that sense molecules outside the cell and activate inside signal transduction pathways and, ultimately, cellular responses.
Receptor tyrosine kinase
the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones.
Ion channel receptors
cell membrane bound receptors. They act through synaptic signaling on electrically excitable cells. The ion channels opening and closing is controlled by neurotransmitters. Ion-channel-linked receptors are also called ligand-gated channels. These membrane-spanning proteins undergo a conformational change when a ligand binds to them so that a "tunnel" is opened through the membrane to allow the passage of a specific molecule. These ligands can be neurotransmitters or peptide hormones, and the molecules that pass through are often ions, such as sodium (Na+) or potassium(K+), which can alter the charge across the membrane. The ion channels, or pores, are opened only for a short time, after which the ligand dissociates from the receptor and the receptor is available once again for a new ligand to bind.
Protein kinase
An enzyme that transfers phosphate groups from ATP to a protein
Protein phosphatase
Enzymes that can rapidly remove phosphate groups from proteins
Second messengers
These messengers differ in the mechanism by which they are produced and removed, as well as their downstream targets and effects
Cyclic AMP
Binding of epinephrine to the plasma membrane of a liver cell elevates the cytosolic concentration of a compound
Adenylyl cyclase
Converts ATP to CAMP in response to an extracellular signal
IP3
DAG
2nd messenger produced by cleavage of a certain kind of phospholipid
Scaffolding proteins
Large relay proteins to which several other relay proteins are simotaneously attached
Apoptosis
Cells that are infected or damaged undergo programmed cell death