Front | Back |
GENERIC NAME:
BRAND NAME:
CLASS:
|
GENERIC NAME:
None
BRAND NAME:
Atropine
CLASS:
Anticholinergic agent
|
MECHANISM OF ACTION:
|
Parasympatholytic: Inhibits action of ache at postganglionic parasympathetic neuroeffector sites. Increases HR in life threatening bradyarrhythmias.
|
INDICATIONS:
|
Hemodynamically unstable Bradycardia, Asystole, Bradycardic,PEA Organophosphate poisoning, bronchospastic pulmonary disorders.
|
CONTRAINDICATIONS:
|
Tachycardia, Hypersensitivity, unstable cardiovascular status in acute hemorrhage and myocardial ischemia, narrow-angle glaucoma.
|
ADVERSE REACTIONS:
|
HA,dizziness,Palpitations, N/V,tachycardia,arrhythmias, anticholinergic effects,paradoxical Bradycardia(slowly or at low doses),flushed,hot,dry skin.
|
List anticholinergic effects.
1.2.3.
|
Blurred vision, dry mouth, urinary retention
|
NOTES ON ADMINISTRATION
|
Pregnancy category C, Moderate doses may cause pupil dilation.
|
INCOMPATABILITIES/DRUG INTERACTIONS:
|
Effects enhanced by antihistamines, procainamide, quinidine, antipsychotics, benzodiazepines, and antidepressants.
|
Potential adverse effects when administered with ??
|
Potential adverse effects when administered with digoxin, cholinergics, physostigmine.
|
DOSE/ROUTE:
ADULT:
|
Asystole and Bradycardic PEA: 1mg IV/IO push may repeat every 3-5 min. up to 3 doses. Unstable Bradycardia: 0.5 mg IV/IO every 3-5 min. not to exceed 3mg total. Organophosphate Poisoning: Extremely large doses (2-4mg or higher)
|
DOSE/ROUTE:
PEDEATRIC:
|
0.02 mg/kg IV/IO push. May double for second dose. Minimum single dose is 0.1 mg. Maximum single dose in child is 0.5mg. Child total dose; 1mg.
|
DOSE/ROUTE:
Adolescent single dose and total dose
|
Adolescent single dose 1mg and total dose 2mg.
|
DOSE/ROUTE:
Child
|
Maximum single dose in child is 0.5mg. Child total dose; 1mg.
|
ONSET OF ACTION:
PEAK EFFECTS:
DURATION OF ACTION:
|
ONSET OF ACTION
Immediate
PEAK EFFECTS:
Rapid to 1-2 minutes
DURATION OF ACTION:
Duration 2-6 hours
|
Drug box supply
|
(4) prefilled 1mg syringes. Total 4mg
(1) 8mg Multidose vial.
|