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Cards In This Set
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Energy-rich nutrients
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CHO, fat and protein
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Catabolism
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The breakdown of energy-rich nutrients to make ATP and energy-poor products (CO2 and H20)
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Anabolism
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The creating of macromolecules (proteins, polysaccharides and nucleic acids) through the breakdown of ATP and precursurs (amino acids,etc)
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Zymology
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Study of fermentation (before biochemistry became a field), enzyme derived from this first area of study in modern biochemistry
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Net Reaction of Glycolysis
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Glucose + 2NAD+ + 2 ADP + 2P = 2 pyruvate + 2 NADH + 2 ATP + 2 H20
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Payoff Phase
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1 NADH and 2 ATP per 3 C molecule (2X)
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ATP --> ATP
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Step 1 and 3
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Step 1 Glycolyisis
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ATP to ADP, - delta G, hexokinase, add phosphate, coupled rxn
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Step 2 Glycolysis
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Phosphohexose Isomeras, rearrangement, keto-enol isomerization, + delta G
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Step 3 Glycolysis
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Phosphfructokinase (PFK-1), negative delta G, Rate-limiting step, allosteric regulation
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Allosteric Regulation in Glycolysis
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High ATP, fatty acids, citrate INHIBITS
High AMP, ADP STIMULATES
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How does ATP inhibit the forward reaction in glycolysis?
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Bind to allosteric site, active site on but doesn't bind there
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Step 4 of Glycolysis
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Aldolase (breakdown or cleavage), 2 trioses, + delta G
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Positive Delta G's in Glycolysis
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Not as positive as delta G's describe because the conditions of the cells change it.
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Step 5 of Glycolysis
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Triose Phosphate Isomerase (TPI), converts dihydroxyacetone to glyceraldehyde 3-phosphate, positive delta G
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