+
Related Flashcards
Related Topics
Cards In This Set
| Front | Back |
|
Virulence Factors
|
Endotoxin (LPS)capsuleadhesinsexotoxins
|
|
Diseases
|
GastroenteritismeningitissepticemiaUTI
|
|
Gastroenteritis
|
-5 groups of Ecoli-transmitted via ingestion of fecally contaminated food/water-infectious dose variable-all cause inflammation in intestinal tract-lead to secretion of prostaglandins which enhances local cAMP production leads to hypersecretion
|
|
Groups of Ecoli that cause gastroenteritis
|
Enteroinvasive ecoli (EIEC)enterotoxigenic ecoli (ETEC)enteroaggregative ecoli (EAEC)enterohemorrhagic ecoli (EHEC)enteropathogenic ecoli (EPEC)
|
|
Enteroinvasive ecoli (EIEC)
|
Acts on large intestine*very low infectious dosesimilarities to shigellaPlnv genes -help with invasion into epithelial cells of colon, allow for intracellular replication, allow for movement via actin filamentsincubation 12-72 hrssymptoms: watery diarrhea, nausea, vomiting, feverusually self limiting
|
|
Enterotoxigenic ecoli (ETEC)
|
Called travelers diarrheaacts on the small intestinehigh infectious dosecauses secretory diarrheano person to person transmissionheat labile enterotoxins (LTI and LTII)heat stable enterotoxin (Sta and STb)colonization factor adhesions (CFAs)
|
