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What are the main components of the extracellular matrix?
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Collagen, Glycosaminoglycans, and glycoproteins
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What happens to collagen once it is released into the Extracellular Matrix?
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An enzyme in the ECM will cleave off the non-helical ends of the collagen so it can polymerize. The collagen will polymerize are arrange from end to end to form fibrils and fibers
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What cells are responsible for producing collagen?
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There are many cells responsible for producing collagen....like fibroblasts, chondrocytes, epithelia cells, Schwan Cells.
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What is the most abundant type of collagen found in mammals?
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Type 1
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What types of collagen in unique to the basement lamina?
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Type 4 collagen
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What are glycoproteins?
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Glycoproteins are globular protein with monosaccarides attached.
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What are the components that make up proteoglycans?
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Proteoglycan is composed of a core protein with glycosaminoglycans (GAGs) attached. They attach matric molecueles
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Fibronectin
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A multifunctional adhesive glycoprotein that binds to ecm matrix components
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What is lamin?
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A multi adhesive glycoprotein
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