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Functions of water
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Medium for transport
facilitate cellular metabolism solvent temperature regulation digestion/elimination tissue lubricant |
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Fluid compartments
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ICF - intracellular, 70% total body water
ECF - extracellular, 30% body water |
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Infants and ECF
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Infants have higher proportions of body fluids. ECF loss causes fluid deficits more easily in infants
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Normal I & O
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1500 - 3500/24H
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Sensible/insensible loss
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Sensible - can be measured: urine, defecation and wounds
insensible - can't be measured: evaporation through skin, water vapor from respiration |
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Electrolyte
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Substance that can break into electrically charged particles called ions
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Cation/anion
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Cation - positively charged ion
anion - negatively charged ion |
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Osmosis
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Major method of transporting body fluids. Water moves through a semi-permiable membrane (like cell walls) from an area of lesser solute concentration to an area of greater solute concentration.
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Isotonic
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A solution with the same osmolarity as plasma
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Active transport
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Movement against concentration gradient, requiring energy (ATP)
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Hydrostatic pressure
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Pressure exerted by the weight of water
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Colloidal (or oncotic) pressure
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The pulling pressure exerted by proteins
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Normal plasma pH
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7.35 - 7.45
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3 mechanisms to regulate pH
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Chemical buffer systems, renal system, respiratory mechanisms
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Body's most common base
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Bicarbonate ion (HCO3-), produced by pancreas, regulated by kidneys
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