Genetics: Meiosis and Genetic Variability

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What is the significance of meiosis?
Significance of meiosis: meiosis introduces genetic variability by genetic recombination
What is genetic recombination?
Genetic recombination is the product of independent assortment and crossing-over, which introduces genetic variability.
What are the differences between meiosis and mitosis?
Answer 3

What does independent assortment generate?
Independent assortment generates genetic variation.
How many copies does a cell have of each somatic chromosome?
A cell has 2 copies of each somatic chromosome- one from mom, one from dad (homologous chromosomes).
With respect to chromosomes, what function does independent assortment perform?
Independent assortment shuffles these chromosomes, and then places only one copy of each into the gamete. This way, the gamete may have chromosome 1 from mom, chromosome 2 from dad, chromosome 3 from dad, ... etc.
Describe the mechanism of independent assortment.
The mechanism of independent assortment is the following: During metaphase I of meiosis, homologous chromosome pair up along the metaphase line in random orientation - sometimes the mom's chromosome is on the left, sometimes it's on the right. During anaphase I of meiosis, the homologous chromosomes are pulled apart. Those on the left will be put into one daughter cell, those on the right will be put into another.
Are genes on different chromosomes randomized due to independent assortment?
Because of independent assortment, genes on different chromosomes are randomized. However, genes on the same chromosome can not be randomized by this mechanism.
Are genes on the same chromosome linked?
Genes on the same chromosome are linked to some extent.
What is "Crossing over"? In which case is crossing over efficient?
Crossing over is a mechanism that reduces linkage. However, crossing over is only efficient when the genes are physically apart from each other on the chromosome.
How does crossing over affect the linkage of genes when they are further apart on the chromosome?
When the genes are further apart on the chromosome, crossing over makes them less linked.
How does the linkage of genes vary with the distance between them?
The physically closer the genes are on the chromosome, the more linked they are.
What is genetic recombination?
Genetic recombination is the process that introduces genetic diversity into the gametes during meiosis.
What are the two processes that make up recombination?
There are 2 processes that make up recombination: independent assortment and crossing over.
When does crossing over occur?
Crossing over occurs during prophase I.