Lecture 10 - What Happens When The Brain Misbehaves

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Cards In This Set

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Freud
- believed heavily on the unconscious mind
- repression of sexual urges and aggressive urges
- Id: instinct/unconscious
- Ego: rational
- Superego: mediates the two / morals
What is neuro-psychoanalysis
- movement within neuroscience and psychoanalysis to combine the insights of both to yield a unified understanding of the mind and brain
What are knownn causes of disorders
- genetic
- progressive cell death
- rapid cell death
- loss of neural connection
What is phenylketurnia (PKU)
- a behavioral disorder
- you need to reduce the levels of phenylalanine
- results in mental retardaton if you leave it untreated
Why is it difficult to diagnose behavioral disorders?
- because people are objective (one person's thoughts may be different from another)
- people are seldom specific in their symptoms
- those that evaluate the symptoms have their own conceptual biases
Why do we avoid investigatting with animal models?
- because they are oversimplified
- many symptoms are cognitive, and very hard to mimick in a lab
What is epidemiology
- the study of the distribution and causes of diseases in human populations
What are the 2 sets of criteria for diagnoses
- ICD-10: WHO classification system
- DSM: APA
Explain the use of brain imaging
- we can't exactly diagnose mental disorders thought brain imaging
- the imaging tools need to be sensitive enough to detect unique features and specific enough to rule out similar conditions
What are the types of organic abnormalities?
- genetic disorders (ex. huntingtons)
- developmental (ex. autism)
- infectious (ex. meningitis)
- NS injuries (ex. brain and spinal cord trauma
- Degenerative Dementias (ex. Alzheimer's)
What do all of those abnormalities include?
- the absense/presense/death of neurons or glia
- neural connections with unusual connections
Explain biochemical abnormalities
- disordered proteins in cell-membrane channels
- low/high # of neuroreceptors
- low/high # of molecules (neurotransmitters/hormones)
What are the types of neurosurgical treatment
- Deep Brain Stimulation
- Stem Cell Therapy
What is Deep Brain Stimulation (DBS)
- where they put an electrode into the brain and stimulate a targeted area to facilitate behavior
- can treat Parkinson's and depression
- the recovery time is long
- you have to keep them on stimulation, or else you risk relapsing
WHat is stem cell therapy
- where we use fetal cells for implanting
- multipotent stem cells from other parts of the body is more effective