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Cards In This Set
| Front | Back |
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Pathogenicity
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Ability to cause disease
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Virulence
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Extent of pathogenicity
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Portals of Entry - Organisms in the body
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Mucous membranes
Skin Parenteral route |
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Parenteral route
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Injection or bloodstream via a vector
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Skin
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Infection or burrowing of a parasite
|
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Mucous membranes are found
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In openings of body
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Preferred portal of entry
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Most likely place to cause disease
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Invading Microbes ID50
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Infectious dose for 50% of test group
Higher ID50- least likely to become sick |
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Invading Microbes LD50
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Lethal Dose for 50% of test population
Higher LD50- least likely to die fro pathogen |
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Adhesins
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Binds to receptors on host cells
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Ligands
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Binds to receptors on host cells
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Virulence Factors
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Adherence ,capsules, cell walls, enzymes
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Cell Wall Virulence Factor - M protein
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Resist phagocytosis And Adherence
streptococcus pyogenes |
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Cell wall virulence factor- Opa protein
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Inhibits T-helper cells
Neisseria gonorrhoea |
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Cell Wall virulence factor- Mycolic acid
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Resists digestion of cell wall
Mycobacterium tuberculosis |
