Microbial Mechanisms of Pathogenicity CH 15

Tortora Funke CAse 

73 cards   |   Total Attempts: 182
  

Cards In This Set

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Pathogenicity
Ability to cause disease
Virulence
Extent of pathogenicity
Portals of Entry - Organisms in the body
Mucous membranes
Skin
Parenteral route
Parenteral route
Injection or bloodstream via a vector
Skin
Infection or burrowing of a parasite
Mucous membranes are found
In openings of body
Preferred portal of entry
Most likely place to cause disease
Invading Microbes ID50
Infectious dose for 50% of test group

Higher ID50- least likely to become sick
Invading Microbes LD50
Lethal Dose for 50% of test population

Higher LD50- least likely to die fro pathogen
Adhesins
Binds to receptors on host cells
Ligands
Binds to receptors on host cells
Virulence Factors
Adherence ,capsules, cell walls, enzymes
Cell Wall Virulence Factor - M protein
Resist phagocytosis And Adherence
streptococcus pyogenes
Cell wall virulence factor- Opa protein
Inhibits T-helper cells
Neisseria gonorrhoea
Cell Wall virulence factor- Mycolic acid
Resists digestion of cell wall
Mycobacterium tuberculosis