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Cards In This Set
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Define Agonist & give an example
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Bind & enhance cell function
A drug which activates a receptor Pethidine |
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Define Antagonist & give an example
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Bind & block cell function
A drug which prevents a receptor from being stimulated naloxone (Narcan) |
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What is meant by the term "half-life" of a drug?
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The time it takes for the plasma concentration of a drug to reach half of its original concentration.
How long it takes for half of the concentration to be eliminated from the bloodstream. |
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Define Pharmacokinetics
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Define Pharmacodynamics
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Physicological changes that occur in pregnancy and the effect they have on drug: ABSORPTION
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ABSORPTION: Decrease in absorption from nausea & vomiting
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Physicological changes that occur in pregnancy and the effect they have on drug: DISTRIBUTION
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DISTRIBUTION: Increase distribution from increase of total body water & increase blood volume.
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Physicological changes that occur in pregnancy and the effect they have on drug: METABOLISM
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METABOLISM: As pregnancy hormones increase they inhibit enxyme activity in the liver.
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Physicological changes that occur in pregnancy and the effect they have on drug: EXCRETION
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EXCRETION: Excretion in enhanced as glomerular filtration is enhanced by 50%
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Define Therapeutic failure
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An adverse drug reaction in which the expected effects do not occur following a prescribed pharmacological treatment
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Define Adverse drug reaction
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Unintended harmful reaction to medication
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