NAVLE toxicology Flashcards

What do you know about NAVLE toxicology? This set of flashcards is entirely on the NAVLE toxicology. Do give it a try, and feel free to take the quiz to test what you understood.

110 cards   |   Total Attempts: 193
  

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Cards In This Set

Front Back
CardioGossypol
  • cotton seed, roots, unprocessed, cumulative 1 mo, rum detoxify until overwhelmed, excrete in bile w/ iron
  • brady, v fib, CHF, anemia (chelate iron), repro (abn sperm), D+, death
  • les: mb none, pale heart, lg liver
  • tx: emesis, AC, cathartic, supp Fe, protein
Cardio/Sk: Ionophores
  • monensin, lasalocid, narasin, ___mycin
  • inc Na, so inc Ca, pos ino, then neg
  • D+ wkns atax dysp tachy, edema pale hrt/mm streaks, red urine
  • H/ox: cardio P/Sh/D/C: skel poultry: combo
  • emesis, ac, cath, Se, Vit E
Skel mm: Macadamia nuts
  • 5-40 nuts for avg dog, factor unknown
  • jt pain, posterior paraly
  • recover 1-2 d, tx: usu, analgesic
Cardio: Nerium (oleander), Thevetia (yel oleander)
  • card glycoside, mb green, dried, inhaled smoke
  • tachy, tachyp,v tach, a fib, mydri, dead in 8 hrs
  • hem, edema
  • slowly excreted for wks, tx decon, KCl, procaine, atropine, propanolol
Cardio: Digitalis (foxglove)
  • dx: digoxin in bl, GI
  • tx: as for oleander
Cardio: apocynum (dogbane)
  • cardiac glycoside
  • apocynin, apocynamarin, pocynein, cymarin
  • tx as oleander
Cardio: asclepias (milkweed)
  • card glyco, cardenolides
  • tachy death in 24 hr
  • tx usu unsuccessful, decon, KCl, procainamide, quinidine
Cardio: rhododendron (azalea), laurel (Kalmia)
  • grayanotoxin, inc Na perm, so dec resting potential
  • brady, wkns, saliv, v+, dysp, death 1-3 d
  • decon, Ca, gluc, quinidine, atropine
Cardio: aconitum (monkshood)
  • diterpine alkaloids, inc Na ch, long repolarization
  • brady, Gi, neuro, convuls, death
Cardio: taxus (yew)
  • alkaloids, cyogenic gly, ephedrine, usu clippings in fall
  • taxines inhib AV conduc, brady, tremor dysp collapse
  • dx: taxine analysis tx: decon w/ ac, epsom salt
Cardio: zigadenus (death camus)
  • steroidal alkaloids
  • brady, open mouth froth coma death
  • dx alkaloid analysis, tx symp
Cardio: veratrum (false hellebore, corn lily)
  • alkaloids, young shoots, spring, death rare, teratogenic
  • brady, v+, tremor
  • tx supp, may recover in 4 hrs
Cardio: Persea (avocado)
  • usu birds, unknown mech
  • resp distress, edema, myocard nec
  • tx symp
Renal: Grape/raisin
  • dog, toxin unknown, renal signs, v+, d+, pain
  • decon, fl, furo, low protein, Ca, and P; P binders, dialysis
Renal: jessamine, jasmine, cestrum, chinese inkberry
  • vit D3 (cholecalciferol), D2 (ergocalciferol) tox
  • also rodenticide, feed mixing error
  • calcification, dysp, washout,PU/PD, azo
  • long T1/2 over 1 mo, tx decon, lavage, calcitonin, furo, pred, low Ca/P, Pbinders