Nephrology Board Review

Jhj

45 cards   |   Total Attempts: 189
  

Cards In This Set

Front Back
In AKI, how much does Creatinine typically rise if it starts at 1
0.5
What are bugs that cause alkaline urine?
Proteus, pseudomonas, ureaplasma
What iatrogenic agents increase specific gravity
Mannitol, IV contrast dye
What metabolite do urine ketones measure? What can be missed due to this?
AcAc (in starvation ketosis, BOB predominates so urine ketones will be negative)
How many RBC need to be present for positive urine dipstick?
1-3
What common vitamin can mask hematuria?
Vitamin C
Causes of red urine
Beets, rifampin, chloroquine
Positive leuk esterace test, sens? spec?
3-5 wbcs; sens 48-68%; spec 17-93%NOT A HELPFUL TEST
What bacteria cause positive nitrites? sens? spec?
Only certain bacteria (e. coli, pseudomonas, klebsiella, proteus); sens 45-60%; spec 85-98%
Combination sens/spec of nitrites + leuk est?
Sens 68-88%; spec: high predictive value
How do you work up hematuria?
1. > 3 rbcs on microscopy twice; if only once, causes: menses, heavy exercise, infection2. kind of rbc- if acanthocytes (spiky rbc) or rbc casts, check for proteinuria- if + proteinuria or CKD, renal consult; if negative, then follow q 3-6 months for proteinuria3. If normal rbc, then do cytology on 3 consecutive days; if +, cystoscopy; if cytology, negative, age > 50, bladder cancer RF, then cysto; if negative, age < 50, without RF, stop there
What are RF for bladder cancer?
Smoking, benzene exposure, long term analgesic use, cyclophosphamide
What are most common causes of sterile pyuria?
Atypical infection (TB, polyomavirus, CMV)AIN, chronic TI nephritis
What are common causes of non-nephrotic range proteinuria ( < 2 gm/d)?
TI disease, renovascular, glomerular diseases
What features of a renal cyst cause concern?
Size > 4 cm; complex features