Pharm Exam ?: Ch 16: Antibiotics & Antifungal, Antiviral...

Antibiotics & Antifungal, Antiviral, and Antiparasitic Agents

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Antibiotics
Substances that kill or inhibit the growth of microorganisms
Broad-spectrum antibiotic
Effective against many microorganisms
Narrow-spectrum antibiotic
Effective against only a few microorganisms
Penicillin
Any antibiotic derived from the Penicillium mold
Cephalosporins
Structurally related to the penicillins. exert their activity against young dividing bacterial cells by interfering with the formation of cell walls
Tetracyclines
Broad-spectrum antibiotics that are effective against many organisms, particularly those infecting the respirator system and soft tissures
Quinolones
Class of orally effective antimicrobial agents that act by inhibiting the bacterial enzyme DNA gyrase
Sulfonamides
More commonly called "the sulfa drugs," combat infection in the body by checking the growth of bacteria and other microorganisms, thus enabling the body's own defenses to cope with the infections. synthetic drugs made to resemble para-aminobenzoic acid (PABA)
Para-aminobenzoic acid (PABA)
Substance that the microorganisms need for the sythesis of folic acid
Fungi
Eukaryotic organisms that contain no chlorophyll or vascular tissue
Virus
Microscopic infectious agent that requires an intact living host cell for metabolism
Hepatitis A
Generally a short lived virus not treated with antiviral agents. contracted orally from contaminated food or water
Hepatitis B
Affects 5% of the worldwide population and may lead to cirrhosis and hepatocellular carcinoma. formerly called serum hepatitis and contracted from blood or bodily fluids. most infected persons do not progress to the chronic form
Hepatitis C
The most common cause of end-stage liver disease. 85% fo those who contract this virus develop the chronic form