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How can drugs be cliassified ?
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-Clinical Indication: antifungal, antispasmodics
-Mechanism of action: diuretics, beta-blocker, antihypertensives -Body system: respiratory drugs, cardiovascular drugs, integumentary system drugs |
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Antidysrhythmics groups
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Group I: fast sodium channel inhibitors, Group II: beta-adrenergic blockers, Group III: prolong cardiac repolarization, and Group IV: calcium channel blockers
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Cardiac glycosides (digoxin) pharm action
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Positive inotropic effect - increases contraction strength
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ACE-inhibitors (catopril
Angiotensin receptor blockers (losartan) Diuretics (furosemide, spironolactone) PHARM ACTION |
Reduce fluid retension, which decreases overstretch of myocardial muscle durring ventricular filling (reduced preload
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ACE-Inhibitors (catopril)
Angiotensin receptor blockers (losartan) Vasodilators (nitrates, hydralazine) Aldosterone antagonist (spironlactone PHARM ACTION |
Reduce systemic BP, which improves efficiency of ventricle to expel blood (reduced afterload
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Low-dose Beta-adrenergic blockers (carvedilol
PHARM ACTION |
Blunt long-term sympathetic stimulation associated with worsening heart failure
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B-type natriuretic peptide (nesiritide) PHARM ACTION
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Augment neurohormonal response to heart failure with vasodilation; reduce fluid retention
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Antidysrhythmic drugs
Ca-channel blockers Beta-adrenergic blockers PHARM ACTION |
Converts to normal sinus rhythm, abolishes dysrhythmia, or controls rate
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Nitrates
Ca-channel blockers (dilatiazem) Beta-adrenergic blockers (propranolol) PHARM ACTION |
Coronary vasodilation and/or lessens work of the heart
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Antiplatelets (aspirin)
Anticoagulants (warfarin) Fibrinolytics (alteplase) PHARM ACTION |
Prevent or treat clot formation in coronary arteries
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Antihyperlipidemics (lovastatin)
PHARM ACTION |
Prevent atherosclerosis and risk for clot formation in coronary arteries
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Drugs that effect Cardiac Output
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Beta blockers, diuretics, CCBs
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Drugs that effect Total Peripheral Resistance
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ACE inhibitors, ARBs, Alpha blockers, Alpha-2-agonists, CCBs, diuretics, sympatholytics, vasodilators
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Diuretics promote
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the formation & excretion of urine, resulting in a loss of excess salt and water from the body by renal excretion
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3 types used to treat HTN
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Thiazide, loop diuretics, and potassium sparing diuretics. Thiazides are recommended as 1st-line drug therapy (for uncomplicated HTN).
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