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Related Flashcards
Cards In This Set
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What drugs are used in the treatment of Psoriasis?
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Acitretin, Tazarotene, Calcipotriene, and Biological agents
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What biological agents are used in the treatment of Psorasis?
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T-cell modulators: Alefacept and Efalizumab
TNF-alpha inhibitors: Etanercept
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What is a profile of Acitretin?
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- Given orally
- Hypervitaminosis A
- Elevation of cholesterol and TG
- Hepatotoxicity
- Teratogenic
- Avoid Ethanol and don't donate blood even 3 years after
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What is some basic profile of Tazarotene?
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It is a prodrug and the active metabolite, tazarotenic acid, binds to retinoic acid receptors and causes gene expression. It could be teratogenic.
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What are side effects of Tazarotene?
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It causes burning and stinging sensation, erythema, and localized edema of skin. Could cause photosensitivity so minimize sunlight
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What are indicaitons of Calcipotriene?
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It is a synthetic vitamin D3 derivative that has been shown to be effective in the treatment of plaque type psoriasis vulgaris of moderate severity. It elevates serum calcium
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What are side effects of Calcipotriene?
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It causes burning, itching, and mild irritation, with dryness and erythema of the treatment area. Could cause ocular irritation
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