Physio EPPP

Physio/pharm EPPP

105 cards   |   Total Attempts: 183
  

Cards In This Set

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Action Potential:
Depolarization triggers an action potential which is an electrical impulse.
What causes an action potential?
Neuron is normally negatively charged, with enough stimulation, sodium channels open up and allow positively charged ions to enter and create depolarization.
What happens after action potential?
After sodium channels close and potassium channels open to release positively charged potassium ion and repolzarize back to negative state.
Acetylcholine/ACh: location in CNS, related disease
In peripheral and CNS. Breakdown of ACh related to Alzhemers etc.
Ach function
In peripheral causes muscles to contract. In CNS involved in REM sleep, sleep wake cycle, memory.
Dopamine: effects on, disease related to
Personality, mood, sleep. Schizophrenia hypothesis of high levels or overactive receptors. Movement: oversensitivity related to Tourettes and Parkinson’s. Mood: reinforce drug use. Cocaine increase dopamine.
Serotonin:
Inhibitory effect. Mood, hunger, aggression, migraine.
Elevated seratonin leads to:
Elevated leads to schizophrenia, autism, restriction/Anorexia.
Low levels of seratonin lead to:
Low levels lead to aggression, depression, suicide, Bulimia, PTSD, OCD.
GABA: type of effect, related to what
Inhibitory effect. Eating, seizure, anxiety, motor, vision. Benzos and CNS depressants reduce effects of GABA.
Low GABA leads related to what diseases/conditions
Low GABA anxiety. Low GABA in Huntington’s disease.
Spinal cord:
Bundles or myelinated axons, dendrites and somas. Info between brain and body, coordinate left/right body and controls simple reflexes
Function of nerves in superior portion of spinal cord:
Nerves in superior portion carry afferent/sensory messages.
Function of nerves in inferior portion of spinal cord:
Nerves in inferior portion transmit efferent/motor messages.
Quadriplegia:
Damage at cervical level. Loss of sensory and voluntary motor function of arms and legs.