Microbiology (catabolic Metabolism) Gluconeogenesis Flashcards

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Many microorganisms cannot carry out photosynthesis and are
Heterotrophs
That Must synthesize
sugarsfrom reduced
Organic molecules rather than from CO2
The synthesis of glucose from noncarbohydrate precursors is called
Gluconeogenesis
Although gluconeogenesis pathway is not identical with
Glycolytic pathway
They do share
7 enzymes
Three glycolytic steps are
Irreversible in the cell
1. Conversion of
Phosphoenolpyruvate to pyruvate
2. Formation of
Fructose 1,6 bisphosphate fromfructose 6-phosphate
3. Phosphorylation of
Glucose
These must be bypassed when pathway is operating
Biosynthetically
For example formation of fructose 1,6- bisphosphate by
Phosphofructokinase is reversed by enzyme fructose bisphosphate
Which is hydrolytically removes phosphate from
Bisphosphate
Usually at least 2 enzymes are involved in the conversion of
Pyruvate to phosphoenolpyruvate
The pathway synthesizes
Fructose as well as glucose
Once glucose and fructose have been formed
Other common sugars can be manufactured