Molecular Biology Course III 2

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For 1000 of years farmers and herders have been
Selectively breeding their plants and animals to produce useful hybrids
Knowledge of genetic mechanisms finally came
As a result of careful lab breeding experiments carried out over last century and a half
By the invention of better microscope in 1890
Allowed the biologist to discover fact of cell division and sexual reproduction
The focus of genetic research was the shifted to
Understanding what really happens in the transmission of hereditary traits from parents to children
A number of hypothesis were suggested
To explain heredity
But George Mendel, a Central European monk
Was the only one who got it more or less right
His idea was published in
1866
But largely went unrecognised
Until 1900
His early adult life was spent
Doing basic genetics research and teaching high school mathematics physics and Greek in Brno
In his later years he became
Abbot of his monastery and put aside his scientific work
While mendel’s research was with
Plants
The basic principle of heredity that he discovered was
Applicable to people and animals because the mechanism of heredity are essentially the same for all complex life forms
Through the cross breeding of pea plant(Pisum Sativum) over many generations
He discovered that certain traits show up in off spring without any blending of parental characteristics
For eg the pea flower is either
Purple or white in colour
The intermediate colours do not appear in the
Off spring of cross pollinated pea plants