"Drug Test 3 GI Flashcards "

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In teaching your peptic ulcer patient about his prescribed medications, you would explain that the drug cimetidine (Tagamet): a) binds to and neutralizes hydrogen ions in the stomach b) allieviates anxiety and stress c) can also be purchased at the drug store as Maalox d) coats the mucosa of the stomach e) reduces gastric acid secretions
E) reduces gastric acid secretions
Which of the following statements by Mrs. H. leads you to believe she has understood how to use bulk-forming laxatives? a) I will mix the medication with 8 ounces of juice and follow it immediately by 8 ounces of juice b) I will mix the dry medication with applesauce c) I will use milk of magnesia in conjunction with this medication until I am having daily BMs d) I will decrease the roughage in my diet while I am using this medication
A) I will mix the medication with 8 ounces of juice and follow it immediately by 8 ounces of juice
As a group, antacids act by: a) reducing gastric acid secretions b) absorbing gastric acid c) stimulating an alkaline secretion d) raising the pH
D) raising the pH
Cimetidine acts to reduce gastric irritation by: a) coating the stomach lining with an insoluble protective coating b) blocking the action of histamine in the parietal cells c) stimulating the release of histamine, which inhibits gastrin d) blocking the production of pepsinogen in the chief cells
B) blocking the action of histamine in the parietal cells
Which of the following statements is correct regarding diphenoxylate hydrochloride (Lomotil)? a) It should be given to pts with infectious diarrhea b) the drug is used to control antibiotic-induced pseudomembranous colitis c) Lomotil is classified as a DEA schedule III drug d) It contains atrophine, which may cause dry mouth and blurred vision
D) It contains atrophine, which may cause dry mouth and blurred vision
Bulk-forming laxatives:   a) produce harmful nutritional SE   b) expand as water is absorbed into the fecal contents   c) empty both the large and small intestines   d) interfere with vitamin A absorption
B) expand as water is absorbed into the fecal contents
Elderly people with impaired renal fxn must use what kinds of products carefully?   a) calcium   b) aluminum   c) magnesium
C) magnesium.   Those with cardiac problems need to avoid antacids containg sodium (Rolaids).
Antacids should be seperated from administration of other drugs by:
At least 1 hour.
How long should antacids be taken for peptic ulcers?   a) it is taken for pain, so you can stop taking it when you are no longer in pain.   b) usually 6-8 weeks; until the ulcer is healed.   c) about 4 weeks
B) usually 6-8 weeks; until the ulcer is healed.   Antacids create a local environment that favors healing.
Which antacids cause constipation:   a) magnesium b) calcium c) aluminum
B&c   most commercial preparations are mixtures to balance effect on GI motility.
Alginic acid (Gaviscon) is used for:   a) GERD b) stool softener c) peptic ulcers d) motion sickness
A) GERD. It is an antacid.   The alginic acid forms a coam that entraps magnesium salts and/or sodium bicarb and floats on top of gastric juices as these juices regurgitate up the esophagus. Hence, it has a protective effect in the esophagus.
Omeprazole (Prilosec) works by:   a) coating the stomach lining with an insoluble protective coating   b) blocking the action of histamine in the parietal cells, causing a dose dependent inhibition of gastric secretion.   c) blocking the production of pepsinogen in the cheif cells   d) suppressing gastric acid secretion by specific irreversible inhibition of the H+/K+ ATPase enzyme system at the secretory surface of the gastric parietal cells.
D) suppressing gastric acid secretion by specific irreversible inhibition of the H+/K+ ATPase enzyme system (termed proton pump inhibitors) at the secretory surface of the gastric parietal cells.   Because they inhibit the final step in gastric acid formation, they inhibit gastric secretion regardless of the stimulus.
Sucralfate (Carafate) is a cytoprotective agent. Can it be taken with food?
No, it is given 1 hour BEFORE meals and at bedtime, but not within a 1/2 hour of antacids.   If you take with food it will bind to the protein in your food and not the protein that makes up the protective layer on your stomach.
Misoprostol (Cytotec) is indicated in:   a) short-term treatment and maintenance therapy for duodenal ulcers   b) GERD   c) prevention of NSAID induced ulcers in patients at high risk of complications from a gastric ulcer.   d) diabetic gastroparesis, symptomatic gastroesophageal reflux, and n/v assoc with emetogenic cancer chemotherapy
C) prevention of NSAID (including aspirin) induced ulcers in patients at high risk of complications from a gastric ulcer.   Misoprostol is a synthetic prostaglandin E1 that has both antisecretory and mucosal protective properties, facilitating regeneration of the mucosa after NSAID-induced injury. It enhances mucous and bicarb secretion.       a - sucralfate (carafate) d - reglan
What pregnancy category is Misoprostol?  
X - can cause uterine contractions   It is used for cervial ripening by vaginal insertion and as an abortifacient.   Sublingual- reduced the frequency of severe postpardum hemorrhage.   (both are UNLABELED uses of the drug)