Trichomonas vaginalis

Trichomonas vaginalis

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Des the morphology of Trichomonas vaginalis
Larger than tri. Tenax Short undulating memb. More granules along costa and axostyle Arranged hydrogenosomes distinguishes T. viag from other Tri Spp. Produces pseudopodia
Where does Trichomonas vaginalis live
Lives in vagina & urethra of women & prostrate seminal vesicles & urethra of men
What is the mode of tranmission of Trichomonas vaginalis
Trans by sex In some cases via semen in artificial insemination
What is the required diagnosis of Trichomonas vaginalis
Recog of trichonomad in secretion from an invitro culture made from vaginal irrigation
What drug is used to treat Trichomonas vaginalis
oral drug metronidazole Sexual partners treated simultaneously to avoid reinfection
What are the symptoms of Trichomonas vaginalis
Some strains cause intense inflammation with itching & white discharge (leukorrhea) In men symp are, may have irritating urethritis or prostratitis
How does Trichomonas vaginalis multiply
Divide by longitudinal fission
Des the metabolism of Trichomonas vaginalis
Trichomo aerotolerant anaerobes degrading carbohydrates incompletely to short chain organic acids & carbon dioxide. use hydrgenosomes in place of mitochondria to produce energy Produce molecular hydrogen in absences of oxygen Pyruvate is produced in cytoplasm by glycolysis Oxidation of pyruvate to acetate is coupled to substrate- level generation of ATP; thus hydrgenosome participate in energy production in cell Metronidazole is reduced by ferrodoxin to form toxic products thus explains how drug works
Is Trichomonas vaginalis asymptomatic
Yes
What 2 things make T. vaginalis differnt from Guiardia
Produce molecular hydrogen in absences of oxygen
What does T. vaginalis use inplace of a mitochondria
Hydrgenosome